James H Cole | MANIFOLD Lab

University of Melbourne visit

Thu, 02 Apr 2026 00:00:00 +0000

From January to April 2026, James went to visit collaborators at the Department of Psychiatry, University of Melbourne. Thanks for being such great hosts!

Investigating the Utility of Explainable Artificial Intelligence for Neuroimaging-Based Dementia Diagnosis and Prognosis

Mon, 02 Feb 2026 00:00:00 +0000

A composite measure of cerebral small vessel disease predicts cognitive change after stroke

Thu, 01 Jan 2026 00:00:00 +0000

Accelerated Brain Aging Identifies Functional Vulnerability Beyond Chronological Age in Multiple Sclerosis

Thu, 01 Jan 2026 00:00:00 +0000

Association of Brain Age With Physical Disability and Cognitive Impairment in People With Multiple Sclerosis of the Same Age

Thu, 01 Jan 2026 00:00:00 +0000

Estimating white matter hyperintensities volume in individuals with stroke using T1-weighted images

Thu, 01 Jan 2026 00:00:00 +0000

Recommendations for reporting findings from analyses using artificial intelligence and machine learning in the Journal of Alzheimer's Disease

Thu, 01 Jan 2026 00:00:00 +0000

The potential of low-field MRI for global dementia care

Thu, 01 Jan 2026 00:00:00 +0000

Chinese community outreach event

Wed, 10 Sep 2025 00:00:00 +0000

Dementia Awareness Day for the London Chinese Community On the 28th June 2025, Dr Jess Jiang (UCL Dementia Research Centre) and Anthi Papouli (UCL Hawkes Institute and member of the MANIFOLD lab) organised a full-day event for the local Chinese community featuring different talks and activities, all with the main goal of providing information on dementia and brain health.

The day featured the following talks:

‘Introduction to Dementia’ – Dr Jess Jiang
‘Understanding Parkinson’s disease dementia and Parkinson’s research at UCL’ – Dr Sabrina Kalam (UCL Dementia Research Centre)
‘Cognitive Stimulation Therapies: An Overview of Treatments for Mild to Moderate Dementia’ – Dr Esther Hui (UCL Division of Psychiatry)
‘Alzheimer’s Disease: from genetics to treatments’ – Dr Maryam Shoai (UCL Institute of Neurology)
We also had an amazing Sensory Stimulation Exercises session led by Zoe Chan (Ebenezer Holistic Services).
We featured booths of services and research including ones from the MANIFOLD lab, Dementia Research Centre, Rare Dementia Support, ‘Photos at the Table’ (Ming Zhu, UCL), Ebenezer Holistic Services, Chinese Welfare Trust and UK Dementia Trials Network.
Finally, we finished the day with a Q&A session with Professor Jason Warren (UCL Dementia Research Centre) and Dr Miguel Rosa-Grilo (UCL Dementia Research Centre).

With 52 attendees coming to the event, our anonymous feedback indicated that 100% of respondents found that the event met their expectations and that it was helpful. Through pre and post surveys, results showed:

9% increase on dementia knowledge using the Dementia Knowledge Assessment Scale, led largely by a 23% increase on the ‘risk and health promotion’ sub-scale
19% increase in respondents agreeing with the statement ‘I feel comfortable discussing dementia with friends and family’
21% increase in respondents agreeing with the statement ‘I would know what to do if I was concerned about my cognitive health in the UK’
50% increase in respondents agreeing with the statement ‘There are support services available in the UK that I can access if I or someone I know gets a diagnosis of dementia’
20% increase in respondents agreeing with the statement ‘I would be interested in participating in research relating to dementia’ Further, 92% of respondents indicated that they would be interested in attending another dementia awareness event.

Throughout the day, we had a brilliant team of volunteers who helped make the event possible – whether through translating, general coordination and background support. A very large thank you to: Islington Chinese Association, Lexi He, Charlotte Wu, Milly Mak, Yuhan Bai, Jenny Huang, Leon Cheung, Ximena Choi, Ming Zhu, Angel Yuen, Hesther Ng, Charlie Harrison, Lucy Core, Lisa Yeung-Donaldson, Eddie Chan, Joe Hung, Roberta McKee-Jackson, Prof Seb Crutch, Christine Chow, Cath Prof Mummery, Prof James Cole, Dr Luci Dobson, and Brenda Bell. This event was kindly funded by the Alzheimer’s Society lab and the UK Dementia Trials Network.

Quantitative susceptibility mapping reveals differences between subtypes of Lewy body dementia

Thu, 04 Sep 2025 00:00:00 +0000

Brain age prediction from MRI scans in neurodegenerative diseases

Fri, 01 Aug 2025 00:00:00 +0000

CUHK visit

Fri, 02 May 2025 00:00:00 +0000

In May 2025 we had a visit from Dr Hanna Lu and her team from the Chinese University of Hong Kong.

Science of Surgery

Fri, 11 Apr 2025 00:00:00 +0000

On the 11th April, members of the MANIFOLD lab ran a stall at the 2025 Hawkes Institute’s Science of Surgery.

Author Response: Sex-Dependent Effects of Cardiometabolic Health and APOE4 on Brain Age

Wed, 01 Jan 2025 00:00:00 +0000

Authors: Sivaniya Subramaniapillai, admin, Ann-Marie G. de Lange

DOI: https://doi.org/10.1212/wnl.0000000000210221

Brain Age Gap Reduction Following Physical Exercise Mirrors Negative Symptom Improvement in Schizophrenia Spectrum Disorders

Wed, 01 Jan 2025 00:00:00 +0000

Authors: Deniz Yilmaz, Sergi Papiol, Daniel Keeser, James H Cole, Berend Malchow, Andrea Schmitt, Peter Falkai, Isabel Maurus, Lukas Roell

DOI: https://doi.org/10.1101/2025.01.08.24319554

Brain Age Is Longitudinally Associated With Sensorimotor Impairment and Mild Cognitive Impairment in Subacute Stroke

Wed, 01 Jan 2025 00:00:00 +0000

Brain-age in ultra-low-field MRI: how well does it work?

Wed, 01 Jan 2025 00:00:00 +0000

Authors: Francesca Biondo, Carly Bennallick, Sophie A. Martin, Lemuel Puglisi, Thomas C. Booth, David A. Wood, Juan Eugenio Iglesias, František Váša, James H Cole

DOI: https://doi.org/10.1101/2025.10.19.25338298

Does restrictive anorexia nervosa impact brain aging? A machine learning approach to estimate age based on brain structure

Wed, 01 Jan 2025 00:00:00 +0000

Authors: Yubraj Gupta, Feliberto de la Cruz, Katrin Rieger, Monica di Giuliano, Christian Gaser, admin, Lauren Breithaupt, Laura M. Holsen, Kamryn T. Eddy, Jennifer J. Thomas, Suheyla Cetin-Karayumak, Marek Kubicki, Elizabeth A. Lawson, Karen K. Miller, Madhusmita Misra, Andy Schumann, Karl-Jürgen Bär

DOI: https://doi.org/10.1016/j.compbiomed.2025.110484

Explainable artificial intelligence for neuroimaging-based dementia diagnosis and prognosis

Wed, 01 Jan 2025 00:00:00 +0000

Authors: Sophie A. Martin, An Zhao, Jiongqi Qu, Phoebe Imms, Andrei Irimia, Frederik Barkhof, admin

DOI: https://doi.org/10.1101/2025.01.13.25320382

Latent Representations of Early Brain Development: A Multivariate Normative Model of Brain Structure and Behaviour

Wed, 01 Jan 2025 00:00:00 +0000

Authors: Mariam Zabihi, Francesca Biondo, Jonathan O’Muircheartaigh, Thomas Wolfers, Sean Deoni, Andre Marquand, Muriel M.K. Bruchhage, James H. Cole

DOI: https://doi.org/10.1101/2025.08.14.668769

Quantitative susceptibility mapping reveals differences between subtypes of Lewy body dementia

Wed, 01 Jan 2025 00:00:00 +0000

Authors: Rohan Bhome, George E C Thomas, Naomi Hannaway, Ivelina Dobreva, Angeliki Zarkali, Karin Shmueli, James H Cole, Rimona S Weil

DOI: https://doi.org/10.1093/brain/awaf325

Regional brain aging patterns reveal disease-specific pathways of neurodegeneration

Wed, 01 Jan 2025 00:00:00 +0000

Authors: Pál Vakli, Béla Weiss, Attila Keresztes, Petra Hermann, admin, Zoltán Vidnyánszky

DOI: https://doi.org/10.1101/2025.11.12.25339989

Repeatability and reproducibility of brain age estimates in multiple sclerosis for three publicly available models

Wed, 01 Jan 2025 00:00:00 +0000

Authors: Lonneke Bos, David R. van Nederpelt, admin, E.M.M. Strijbis, B. Moraal, J.P.A. Kuijer, B.M.J. Uitdehaag, F. Barkhof, A.M. Wink, H. Vrenken, B. Jasperse

DOI: https://doi.org/10.1016/j.ynirp.2025.100252

SLaM Image Bank – a real-world diverse London cohort linking brain MRI to electronic mental health and dementia records for the development of clinical decision support tools using artificial intelligence

Wed, 01 Jan 2025 00:00:00 +0000

Authors: Ashwin V. Venkataraman, Paul Wright, Amelia Jewell, Christopher Webb, Yini Zhang, Soha K. Patil, M. Jorge Cardoso, admin, Matthew J. Kempton, Charles R. Marshall, Mitul A. Mehta, Christoph Mueller, Timothy R. Nicholson, Thomas A. Pollak, Timothy Rittman, Zeynep Sahin, Ana B. Solana, Daniel R. Stahl, František Váša, Allan H Young, Steve Williams, Robert Stewart, Dag Aarsland

DOI: https://doi.org/10.1101/2025.01.07.25319950

Structural similarity networks reveal brain vulnerability in dementia

Wed, 01 Jan 2025 00:00:00 +0000

Authors: Marcella Montagnese, Amir Ebneabbasi, Natalia García‐San‐Martín, Clara Pecci‐Terroba, Rafael Romero‐García, Sarah E. Morgan, admin, Jakob Seidlitz, Timothy Rittman, Richard A. I. Bethlehem

DOI: https://doi.org/10.1002/alz.70973

Towards precision MRI biomarkers in epilepsy with normative modelling

Wed, 01 Jan 2025 00:00:00 +0000

Authors: Remika Mito, James H Cole, Sila Genc, Graeme D Jackson, Andrew Zalesky

DOI: https://doi.org/10.1093/brain/awaf090

Lab photo

Fri, 22 Nov 2024 00:00:00 +0000

We had a visit from a photographer!

Personalizing progressive changes to brain structure in Alzheimers disease using normative modeling

Thu, 05 Sep 2024 00:00:00 +0000

Accelerated Aging after Traumatic Brain Injury: An ENIGMA Multi‐Cohort Mega‐Analysis

Mon, 01 Jan 2024 00:00:00 +0000

Authors: Emily L Dennis, Samantha Vervoordt, Maheen M Adamson, Amiri Houshang, Erin D Bigler, Karen Caeyenberghs, James H Cole, Kristen Dams‐O’Connor, Evelyn M Deutscher, Ekaterina Dobryakova, Helen M Genova, Jordan H Grafman, Asta K Håberg, Torgeir Hellstrøm, Andrei Irimia, Vassilis E Koliatsos, Hannah M Lindsey, Abigail Livny, David K Menon, Tricia L Merkley, Abdalla Z Mohamed, Stefania Mondello, Martin M Monti, Virginia FJ Newcombe, Mary R Newsome, Jennie Ponsford, Amanda Rabinowitz, Hanne Smevik, Gershon Spitz, Umesh M Venkatesan, Lars T Westlye, Ross Zafonte, Paul M Thompson, Elisabeth A Wilde, Alexander Olsen, Frank G Hillary

DOI: https://doi.org/10.1002/ana.26952

Assessing brain involvement in Fabry disease with deep learning and the brain‐age paradigm

Mon, 01 Jan 2024 00:00:00 +0000

Authors: Alfredo Montella, Mario Tranfa, Alessandra Scaravilli, Frederik Barkhof, Arturo Brunetti, admin, Michela Gravina, Stefano Marrone, Daniele Riccio, Eleonora Riccio, Carlo Sansone, Letizia Spinelli, Maria Petracca, Antonio Pisani, Sirio Cocozza, Giuseppe Pontillo

DOI: https://doi.org/10.1002/hbm.26599

Exploratory analysis of biological age measures in a remyelination clinical trial

Mon, 01 Jan 2024 00:00:00 +0000

Authors: Christopher E McMurran, Ermelinda de Meo, Nick G Cunniffe, J William L Brown, Ferran Prados, Baris Kanber, James H Cole, Alasdair J Coles, Sara Hägg, Declan T Chard

DOI: https://doi.org/10.1093/braincomms/fcaf032

Greater lesion damage is bidirectionally related with accelerated brain aging after stroke

Mon, 01 Jan 2024 00:00:00 +0000

Authors: Mahir H. Khan, Octavio Marin-Pardo, Stuti Chakraborty, Michael R. Borich, Mayerly Castillo, admin, Steven C. Cramer, Miranda R. Donnelly, Emily E. Fokas, Niko H. Fullmer, Jeanette R. Gumarang, Leticia Hayes, Hosung Kim, Amisha Kumar, Emily A. Marks, Emily R. Rosario, Heidi M. Schambra, Nicolas Schweighofer, Grace C. Song, Myriam Taga, Bethany P. Tavener, Carolee J. Winstein, Sook-Lei Liew

DOI: https://doi.org/10.1101/2024.12.13.24319014

Personalizing progressive changes to brain structure in Alzheimer's disease using normative modeling

Mon, 01 Jan 2024 00:00:00 +0000

Authors: Serena Verdi, Saige Rutherford, Charlotte Fraza, Duygu Tosun, Andre Altmann, Lars Lau Raket, Jonathan M. Schott, Andre F. Marquand, admin

DOI: https://doi.org/10.1002/alz.14174

Volume and Distribution of White Matter Hyperintensities in Rheumatoid Arthritis and Ulcerative Colitis Patients

Mon, 01 Jan 2024 00:00:00 +0000

Brain Matters: Exploring Bias in AI for Neuroimaging Research

Sun, 01 Oct 2023 00:00:00 +0000

Interpretable Alzheimer’s Disease Classification Via a Contrastive Diffusion Autoencoder

Mon, 05 Jun 2023 00:00:00 +0000

Revealing Individual Neuroanatomical Heterogeneity in Alzheimer Disease Using Neuroanatomical Normative Modeling

Mon, 01 May 2023 00:00:00 +0000

Interpretable deep learning for dementia: a systematic review

Fri, 03 Feb 2023 00:00:00 +0000

A neuroimaging measure to capture heterogeneous patterns of atrophy in Parkinson’s disease and dementia with Lewy bodies

Sun, 01 Jan 2023 00:00:00 +0000

Authors: R Bhome, S Verdi, SA Martin, N Hannaway, I Dobreva, NP Oxtoby, Castro Leal G, S Rutherford, AF Marquand, RS Weil, JH Cole

DOI: https://doi.org/10.1101/2023.08.01.23293480

Accelerated Aging after Traumatic Brain Injury: an ENIGMA Multi-Cohort Mega-Analysis

Sun, 01 Jan 2023 00:00:00 +0000

Authors: Emily L Dennis, Samantha Vervoordt, Maheen M Adamson, Houshang Amiri, Erin D Bigler, Karen Caeyenberghs, James H Cole, Kristen Dams-O’Connor, Evelyn M Deutscher, Ekaterina Dobryakova, Helen M Genova, Jordan H Grafman, Asta K Håberg, Torgeir Hollstrøm, Andrei Irimia, Vassilis E Koliatsos, Hannah M Lindsey, Abigail Livny, David K Menon, Tricia L Merkley, Abdalla Z Mohamed, Stefania Mondello, Martin M Monti, Virginia FJ Newcome, Mary R Newsome, Jennie Ponsford, Amanda Rabinowitz, Hanne Smevik, Gershon Spitz, Umesh M Vankatesan, Lars T Westlye, Ross Zafonte, Paul M Thompson, Elisabeth A Wilde, Alexander Olsen, Frank G Hillary

DOI: https://doi.org/10.1101/2023.10.16.562638

Association of Brain Age, Lesion Volume, and Functional Outcome in Patients With Stroke

Sun, 01 Jan 2023 00:00:00 +0000

Authors: Sook-Lei Liew, Nicolas Schweighofer, admin, Artemis Zavaliangos-Petropulu, Bethany P. Tavenner, Laura K.M. Han, Tim Hahn, Lianne Schmaal, Miranda R. Donnelly, Jessica N. Jeong, Zhizhuo Wang, Aisha Abdullah, Jun H. Kim, Alexandre Hutton, Giuseppe Barisano, Michael R. Borich, Lara A. Boyd, Amy Brodtmann, Cathrin M. Buetefisch, Winston D. Byblow, Jessica M. Cassidy, Charalambos C. Charalambous, Valentina Ciullo, Adriana Bastos Conforto, Rosalia Dacosta-Aguayo, Julie A. DiCarlo, Martin Domin, Adrienne N. Dula, Natalia Egorova-Brumley, Wuwei Feng, Fatemeh Geranmayeh, Chris M. Gregory, Colleen A. Hanlon, Kathryn Hayward, Jess A. Holguin, Brenton Hordacre, Neda Jahanshad, Steven A. Kautz, Mohamed Salah Khlif, Hosung Kim, Amy Kuceyeski, David J. Lin, Jingchun Liu, Martin Lotze, Bradley J. MacIntosh, John L. Margetis, Maria Mataro, Feroze B. Mohamed, Emily R. Olafson, Gilsoon Park, Fabrizio Piras, Kate P. Revill, Pamela Roberts, Andrew D. Robertson, Nerses Sanossian, Heidi M. Schambra, Na Jin Seo, Surjo R. Soekadar, Gianfranco Spalletta, Cathy M. Stinear, Myriam Taga, Wai Kwong Tang, Greg T. Thielman, Daniela Vecchio, Nick S. Ward, Lars T. Westlye, Carolee J. Winstein, George F. Wittenberg, Steven L. Wolf, Kristin A. Wong, Chunshui Yu, Steven C. Cramer, Paul M. Thompson

DOI: https://doi.org/10.1212/wnl.0000000000207219

Brain-predicted age difference estimated using DeepBrainNet is significantly associated with pain and function—a multi-institutional and multiscanner study

Sun, 01 Jan 2023 00:00:00 +0000

Authors: Pedro A. Valdes-Hernandez, Chavier Laffitte Nodarse, Alisa J. Johnson, Soamy Montesino-Goicolea, Vishnu Bashyam, Christos Davatzikos, Julio A. Peraza, admin, Zhiguang Huo, Roger B. Fillingim, Yenisel Cruz-Almeida

DOI: https://doi.org/10.1097/j.pain.0000000000002984

Comparison of volumetric brain analysis in subjects with rheumatoid arthritis and ulcerative colitis

Sun, 01 Jan 2023 00:00:00 +0000

Authors: Jennifer G. Cox, Marius de Groot, Matthew J. Kempton, Steven C. R. Williams, admin

DOI: https://doi.org/10.1101/2023.03.08.23286980

Comprehensive assessment of sleep duration, insomnia, and brain structure within the UK Biobank cohort

Sun, 01 Jan 2023 00:00:00 +0000

Authors: Aleks Stolicyn, Laura M Lyall, Donald M Lyall, Nikolaj Kjær Høier, Mark J Adams, Xueyi Shen, James H Cole, Andrew M McIntosh, Heather C Whalley, Daniel J Smith

DOI: https://doi.org/10.1093/sleep/zsad274

Factors affecting the labelling accuracy of brain MRI studies relevant for deep learning abnormality detection

Sun, 01 Jan 2023 00:00:00 +0000

Authors: Matthew Benger, David A. Wood, Sina Kafiabadi, Aisha Al Busaidi, Emily Guilhem, Jeremy Lynch, Matthew Townend, Antanas Montvila, Juveria Siddiqui, Naveen Gadapa, Gareth Barker, Sebastian Ourselin, admin, Thomas C. Booth

DOI: https://doi.org/10.3389/fradi.2023.1251825

Interpretable machine learning for dementia: A systematic review

Sun, 01 Jan 2023 00:00:00 +0000

Authors: Sophie A. Martin, Florence J. Townend, Frederik Barkhof, James H. Cole

DOI: https://doi.org/10.1002/alz.12948

Personalising Alzheimer’s Disease progression using brain atrophy markers

Sun, 01 Jan 2023 00:00:00 +0000

Authors: Serena Verdi, Saige Rutherford, Charlotte Fraza, Duygu Tosun, Andre Altmann, Lars Lau Raket, Jonathan M. Schott, Andre F. Marquand, admin

DOI: https://doi.org/10.1101/2023.06.15.23291418

Revealing Individual Neuroanatomical Heterogeneity in Alzheimer Disease Using Neuroanatomical Normative Modeling

Sun, 01 Jan 2023 00:00:00 +0000

The value of arterial spin labelling perfusion MRI in brain age prediction

Sun, 01 Jan 2023 00:00:00 +0000

Authors: Mathijs B. J. Dijsselhof, Michelle Barboure, Michael Stritt, Wibeke Nordhøy, Alle Meije Wink, Dani Beck, Lars T. Westlye, admin, Frederik Barkhof, Henk J. M. M. Mutsaerts, Jan Petr

DOI: https://doi.org/10.1002/hbm.26242

Brain-age is associated with progression to dementia in memory clinic patients

Mon, 01 Aug 2022 00:00:00 +0000

Thalamic white matter macrostructure and subnuclei volumes in Parkinson’s disease depression

Mon, 10 Jan 2022 00:00:00 +0000

A meta-analysis of structural MRI studies of the brain in systemic lupus erythematosus (SLE)

Sat, 01 Jan 2022 00:00:00 +0000

Accurate brain‐age models for routine clinical MRI examinations

Sat, 01 Jan 2022 00:00:00 +0000

Authors: David A. Wood, Sina Kafiabadi, Ayisha Al Busaidi, Emily Guilhem, Antanas Montvila, Jeremy Lynch, Matthew Townend, Siddharth Agarwal, Asif Mazumder, Gareth J. Barker, Sebastien Ourselin, admin, Thomas C. Booth

DOI: https://doi.org/10.1016/j.neuroimage.2022.118871

An uncertainty-aware, shareable, and transparent neural network architecture for brain-age modeling

Sat, 01 Jan 2022 00:00:00 +0000

Authors: Tim Hahn, Jan Ernsting, Nils R. Winter, Vincent Holstein, Ramona Leenings, Marie Beisemann, Lukas Fisch, Kelvin Sarink, Daniel Emden, Nils Opel, Ronny Redlich, Jonathan Repple, Dominik Grotegerd, Susanne Meinert, Jochen G. Hirsch, Thoralf Niendorf, Beate Endemann, Fabian Bamberg, Thomas Kröncke, Robin Bülow, Henry Völzke, Oyunbileg von Stackelberg, Ramona Felizitas Sowade, Lale Umutlu, Börge Schmidt, Svenja Caspers, Harald Kugel, Tilo Kircher, Benjamin Risse, Christian Gaser, admin, Udo Dannlowski, Klaus Berger

DOI: https://doi.org/10.1126/sciadv.abg9471

Brain ageing in schizophrenia: evidence from 26 international cohorts via the ENIGMA Schizophrenia consortium

Sat, 01 Jan 2022 00:00:00 +0000

Authors: Constantinos Constantinides, Laura K. M. Han, Clara Alloza, Linda Antonella Antonucci, Celso Arango, Rosa Ayesa-Arriola, Nerisa Banaj, Alessandro Bertolino, Stefan Borgwardt, Jason Bruggemann, Juan Bustillo, Oleg Bykhovski, Vince Calhoun, Vaughan Carr, Stanley Catts, Young-Chul Chung, Benedicto Crespo-Facorro, Covadonga M. Díaz-Caneja, Gary Donohoe, Stefan Du Plessis, Jesse Edmond, Stefan Ehrlich, Robin Emsley, Lisa T. Eyler, Paola Fuentes-Claramonte, Foivos Georgiadis, Melissa Green, Amalia Guerrero-Pedraza, Minji Ha, Tim Hahn, Frans A. Henskens, Laurena Holleran, Stephanie Homan, Philipp Homan, Neda Jahanshad, Joost Janssen, Ellen Ji, Stefan Kaiser, Vasily Kaleda, Minah Kim, Woo-Sung Kim, Matthias Kirschner, Peter Kochunov, Yoo Bin Kwak, Jun Soo Kwon, Irina Lebedeva, Jingyu Liu, Patricia Mitchie, Stijn Michielse, David Mothersill, Bryan Mowry, Víctor Ortiz-García de la Foz, Christos Pantelis, Giulio Pergola, Fabrizio Piras, Edith Pomarol-Clotet, Adrian Preda, Yann Quidé, Paul E. Rasser, Kelly Rootes-Murdy, Raymond Salvador, Marina Sangiuliano, Salvador Sarró, Ulrich Schall, André Schmidt, Rodney J. Scott, Pierluigi Selvaggi, Kang Sim, Antonin Skoch, Gianfranco Spalletta, Filip Spaniel, Sophia I. Thomopoulos, David Tomecek, Alexander S. Tomyshev, Diana Tordesillas-Gutiérrez, Therese van Amelsvoort, Javier Vázquez-Bourgon, Daniela Vecchio, Aristotle Voineskos, Cynthia S. Weickert, Thomas Weickert, Paul M. Thompson, Lianne Schmaal, Theo G. M. van Erp, Jessica Turner, admin, Rosa Ayesa-Arriola, Stefan Du Plessis, Yoo Bin Kwak, Víctor Ortiz-García de la Foz, Therese van Amelsvoort, Theo G. M. van Erp, Danai Dima, Esther Walton

DOI: https://doi.org/10.1038/s41380-022-01897-w

Cognitive and behavioural but not motor impairment increases brain age in amyotrophic lateral sclerosis

Sat, 01 Jan 2022 00:00:00 +0000

Authors: Andreas Hermann, Gaël Nils Tarakdjian, Anna Gesine Marie Temp, Elisabeth Kasper, Judith Machts, Jörn Kaufmann, Stefan Vielhaber, Johannes Prudlo, James H Cole, Stefan Teipel, Martin Dyrba

DOI: https://doi.org/10.1093/braincomms/fcac239

Cross-Sectional Brain-Predicted Age Differences in Community-Dwelling Middle-Aged and Older Adults with High Impact Knee Pain

Sat, 01 Jan 2022 00:00:00 +0000

Authors: Alisa J Johnson, Taylor Buchanan, Chavier Laffitte Nodarse, Pedro A Valdes Hernandez, Zhiguang Huo, James H Cole, Thomas W Buford, Roger B Fillingim, Yenisel Cruz-Almeida

DOI: https://doi.org/10.2147/jpr.s384229

Deep learning models for triaging hospital head MRI examinations

Sat, 01 Jan 2022 00:00:00 +0000

DOI: https://doi.org/10.1016/j.media.2022.102391

Global brain health modulates the impact of lesion damage on post-stroke sensorimotor outcomes

Sat, 01 Jan 2022 00:00:00 +0000

Authors: Sook-Lei Liew, Nicolas Schweighofer, admin, Artemis Zavaliangos-Petropulu, Bethany P. Lo, Laura K.M. Han, Tim Hahn, Lianne Schmaal, Miranda R. Donnelly, Jessica N. Jeong, Zhizhuo Wang, Aisha Abdullah, Jun H. Kim, Alexandre Hutton, Giuseppe Barisano, Michael R. Borich, Lara A. Boyd, Amy Brodtmann, Cathrin M. Buetefisch, Winston D. Byblow, Jessica M. Cassidy, Charalambos C. Charalambous, Valentina Ciullo, Adriana B. Conforto, Rosalia Dacosta-Aguayo, Julie A. DiCarlo, Martin Domin, Adrienne N. Dula, Natalia Egorova-Brumley, Wuwei Feng, Fatemeh Geranmayeh, Chris M. Gregory, Colleen A. Hanlon, Jess A. Holguin, Brenton Hordacre, Neda Jahanshad, Steven A. Kautz, Mohamed Salah Khlif, Hosung Kim, Amy Kuceyeski, David J. Lin, Jingchun Liu, Martin Lotze, Bradley J. MacIntosh, John L. Margetis, Maria Mataro, Feroze B. Mohamed, Emily R. Olafson, Gilsoon Park, Fabrizio Piras, Kate P. Revill, Pamela Roberts, Andrew D. Robertson, Nerses Sanossian, Heidi M. Schambra, Na Jin Seo, Surjo R. Soekadar, Gianfranco Spalletta, Cathy M. Stinear, Myriam Taga, Wai Kwong Tang, Greg T. Thielman, Daniela Vecchio, Nick S. Ward, Lars T. Westlye, Carolee J. Winstein, George F. Wittenberg, Steven L. Wolf, Kristin A. Wong, Chunshui Yu, Steven C. Cramer, Paul M. Thompson

DOI: https://doi.org/10.1101/2022.04.27.489791

Publisher Correction: Brain charts for the human lifespan

Sat, 01 Jan 2022 00:00:00 +0000

Authors: R. A. I. Bethlehem, J. Seidlitz, S. R. White, J. W. Vogel, K. M. Anderson, C. Adamson, S. Adler, G. S. Alexopoulos, E. Anagnostou, A. Areces-Gonzalez, D. E. Astle, B. Auyeung, M. Ayub, J. Bae, G. Ball, S. Baron-Cohen, R. Beare, S. A. Bedford, V. Benegal, F. Beyer, J. Blangero, M. Blesa Cábez, J. P. Boardman, M. Borzage, J. F. Bosch-Bayard, N. Bourke, V. D. Calhoun, M. M. Chakravarty, C. Chen, C. Chertavian, G. Chetelat, Y. S. Chong, J. H. Cole, A. Corvin, M. Costantino, E. Courchesne, F. Crivello, V. L. Cropley, J. Crosbie, N. Crossley, M. Delarue, R. Delorme, S. Desrivieres, G. A. Devenyi, M. A. Di Biase, R. Dolan, K. A. Donald, G. Donohoe, K. Dunlop, A. D. Edwards, J. T. Elison, C. T. Ellis, J. A. Elman, L. Eyler, D. A. Fair, E. Feczko, P. C. Fletcher, P. Fonagy, C. E. Franz, L. Galan-Garcia, A. Gholipour, J. Giedd, J. H. Gilmore, D. C. Glahn, I. M. Goodyer, P. E. Grant, N. A. Groenewold, F. M. Gunning, R. E. Gur, R. C. Gur, C. F. Hammill, O. Hansson, T. Hedden, A. Heinz, R. N. Henson, K. Heuer, J. Hoare, B. Holla, A. J. Holmes, R. Holt, H. Huang, K. Im, J. Ipser, C. R. Jack, A. P. Jackowski, T. Jia, K. A. Johnson, P. B. Jones, D. T. Jones, R. S. Kahn, H. Karlsson, L. Karlsson, R. Kawashima, E. A. Kelley, S. Kern, K. W. Kim, M. G. Kitzbichler, W. S. Kremen, F. Lalonde, B. Landeau, S. Lee, J. Lerch, J. D. Lewis, J. Li, W. Liao, C. Liston, M. V. Lombardo, J. Lv, C. Lynch, T. T. Mallard, M. Marcelis, R. D. Markello, S. R. Mathias, B. Mazoyer, P. McGuire, M. J. Meaney, A. Mechelli, N. Medic, B. Misic, S. E. Morgan, D. Mothersill, J. Nigg, M. Q. W. Ong, C. Ortinau, R. Ossenkoppele, M. Ouyang, L. Palaniyappan, L. Paly, P. M. Pan, C. Pantelis, M. M. Park, T. Paus, Z. Pausova, D. Paz-Linares, A. Pichet Binette, K. Pierce, X. Qian, J. Qiu, A. Qiu, A. Raznahan, T. Rittman, A. Rodrigue, C. K. Rollins, R. Romero-Garcia, L. Ronan, M. D. Rosenberg, D. H. Rowitch, G. A. Salum, T. D. Satterthwaite, H. L. Schaare, R. J. Schachar, A. P. Schultz, G. Schumann, M. Schöll, D. Sharp, R. T. Shinohara, I. Skoog, C. D. Smyser, R. A. Sperling, D. J. Stein, A. Stolicyn, J. Suckling, G. Sullivan, Y. Taki, B. Thyreau, R. Toro, N. Traut, K. A. Tsvetanov, N. B. Turk-Browne, J. J. Tuulari, C. Tzourio, É. Vachon-Presseau, M. J. Valdes-Sosa, P. A. Valdes-Sosa, S. L. Valk, T. van Amelsvoort, S. N. Vandekar, L. Vasung, L. W. Victoria, S. Villeneuve, A. Villringer, P. E. Vértes, K. Wagstyl, Y. S. Wang, S. K. Warfield, V. Warrier, E. Westman, M. L. Westwater, H. C. Whalley, A. V. Witte, N. Yang, B. Yeo, H. Yun, A. Zalesky, H. J. Zar, A. Zettergren, J. H. Zhou, H. Ziauddeen, A. Zugman, X. N. Zuo, C. Rowe, G. B. Frisoni, A. Pichet Binette, E. T. Bullmore, A. F. Alexander-Bloch

DOI: https://doi.org/10.1038/s41586-022-05300-0

Revealing Individual Neuroanatomical Heterogeneity in Alzheimer’s Disease

Sat, 01 Jan 2022 00:00:00 +0000

Authors: Serena Verdi, Seyed Mostafa Kia, Keir Yong, Duygu Tosun, Jonathan M. Schott, Andre F. Marquand, admin

DOI: https://doi.org/10.1101/2022.06.30.22277053

Sex differences in predictors and regional patterns of brain age gap estimates

Sat, 01 Jan 2022 00:00:00 +0000

Authors: Nicole Sanford, Ruiyang Ge, Mathilde Antoniades, Amirhossein Modabbernia, Shalaila S. Haas, Heather C. Whalley, Liisa Galea, Sebastian G. Popescu, admin, Sophia Frangou

DOI: https://doi.org/10.1002/hbm.25983

Tissue volume estimation and age prediction using rapid structural brain scans

Sat, 01 Jan 2022 00:00:00 +0000

Authors: Harriet Hobday, admin, Ryan A. Stanyard, Richard E. Daws, Vincent Giampietro, Owen O’Daly, Robert Leech, František Váša

DOI: https://doi.org/10.1101/2022.01.19.476615

Beyond the average patient: how neuroimaging models can address heterogeneity in dementia

Fri, 01 Oct 2021 00:00:00 +0000

Associations between alcohol use and accelerated biological ageing